Harness your skin's natural repair mechanisms with polynucleotide therapy. This regenerative treatment stimulates cellular renewal, improves skin quality from within, and is particularly effective for delicate areas like the under-eyes and for skin affected by hormonal changes.
Polynucleotides are great for skin regeneration, hydration, and improving skin texture – especially around delicate areas.
We recommend a course of 2-3 treatments spaced 2-4 weeks apart, followed by a maintenance treatment every 6-12 months for best results.
Polynucleotides (PNs) are chains of nucleotides, the building blocks of DNA, derived from salmon or trout DNA. When injected into the skin, they work at a cellular level to stimulate fibroblasts (the cells that produce collagen and elastin), promote tissue repair, and improve overall skin quality.
Unlike fillers that add volume, or toxin that relaxes muscles, polynucleotides work by regenerating your skin from within. They improve hydration, elasticity, and texture by encouraging your skin to repair and renew itself naturally. This makes them particularly valuable for areas where traditional treatments may be less suitable.
Polynucleotides stimulate fibroblast activity, increase collagen and elastin production, improve hydration at a cellular level, and have anti-inflammatory and antioxidant properties. They essentially give your skin the tools it needs to repair and rejuvenate itself, resulting in healthier, more resilient skin over time.
Polynucleotides are ideal for anyone seeking genuine skin improvement rather than just cosmetic enhancement. They're particularly effective for:
The treatment isn't suitable during pregnancy or breastfeeding, or for those with fish allergies (as the product is derived from salmon/trout DNA). Sarah will assess your suitability during consultation.
Polynucleotides can be used across multiple areas to address specific skin concerns at the source.
Improve dark circles, crepey skin, fine lines, and hollowing in this delicate area where traditional fillers may not be suitable.
Overall skin quality improvement – hydration, texture, fine lines, and elasticity across the entire face.
Address crepey neck skin, horizontal lines, and loss of firmness that often betrays age.
Rejuvenate sun-damaged chest skin, improve texture, and reduce fine lines and crepiness.
Improve thinning, crepey hand skin and restore a more youthful appearance to often-neglected hands.
Help improve the appearance of acne scars and other scarring through tissue regeneration.
During perimenopause and menopause, declining oestrogen levels cause skin to become thinner, drier, less elastic, and slower to heal. Polynucleotides directly address these concerns by stimulating the skin's own repair mechanisms, boosting hydration, and improving collagen production. Many women find this treatment transformative for hormonal skin changes that don't respond well to topical products alone.
Polynucleotides work best as a course of treatments. A typical protocol is:
Sarah will recommend a personalised treatment plan based on your skin's needs and goals.
Your journey starts with a thorough consultation where Sarah assesses your skin quality, discusses your concerns, and determines if polynucleotides are the right treatment for you. She'll explain the process and set realistic expectations.
Treatment takes 30-45 minutes. Topical numbing cream is applied beforehand for comfort. Using a fine needle or cannula, Sarah precisely injects the product into the targeted areas using techniques tailored to each zone.
Unlike fillers, results are gradual – you're stimulating your skin to regenerate, which takes time. Initial improvement may be visible after 2-3 weeks, with optimal results seen after completing the full course. Results continue to improve over the following months.
Results from a full course typically last 6-12 months. Because the treatment stimulates genuine skin improvement, the benefits can be longer-lasting than some temporary treatments. Maintenance sessions help sustain results.
Downtime is minimal but varies by area. Expect some redness, swelling, and possible small bumps at injection sites for 24-72 hours. The under-eye area may swell more noticeably. Bruising is possible, particularly around the eyes, and may take 7-10 days to resolve. Most clients feel comfortable returning to normal activities the next day, though you may want to avoid important events for a few days.
Following these guidelines will help you heal well and optimise results:
Sarah will provide detailed written aftercare instructions tailored to your treatment areas.
Polynucleotides have an excellent safety profile. They're biocompatible and gradually absorbed by the body. As with any injectable treatment, there are some risks to be aware of.
Swelling, redness, tenderness at injection sites, small bumps (usually resolve within days)
Bruising (especially around eyes), temporary numbness, mild discomfort
Infection, allergic reaction (particularly in those with fish allergies – please inform Sarah)
Note: Polynucleotides are derived from salmon/trout DNA. If you have a fish allergy, please inform Sarah before treatment.
Polynucleotides combine beautifully with other skin-quality treatments for comprehensive rejuvenation.
Ready to Begin?
Start with a consultation where Sarah will assess your skin, discuss your concerns, and determine if polynucleotides are right for you. Discover how regenerative treatment can transform your skin from within.
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